grant

Role of the inositol polyphosphate 4-phosphatase type 2 in human breast cancer [ 2010 - 2012 ]

Also known as: Identification of a novel regulator of breast cancer

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/606621]

Researchers: Prof Christina Mitchell (Principal investigator) ,  Prof Catriona Mclean

Brief description Breast cancer is the most invasive cancer in females, affecting 1 in 9 women before the age of 85. Normally cells only divide when they receive a stimulus from a hormone or growth factor. The PI3K pathway responds to these stimuli and has been implicated in cancer when cells divide uncontrollably and invade surrounding tissue. We have identified a potential cancer suppressing gene, 4-ptase-2 that turns off the PI3K growth signals. We aim to characterize the role of 4-ptase-2 in breast cancer.

Funding Amount $AUD 611,032.15

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857