Role of IL-3 in allergic inflammation: modulation of basophils, mast cells, eosinophils and remodelling in asthma. [ 2008 - 2010 ]

Research Grant

Researchers: Prof Ian Young (Principal investigator) ,  Prof Paul Foster ,  The Australian National University (Managed by)

Brief description Asthma is an important disease in the Australian community. We will investigate how the underlying inflammation in this disease is controlled and will focus our studies on a hormone-like regulator of the immune system called interleukin-3. Our hypothesis is that interleukin-3 regulates basophils, mast cells and remodelling of the airways which are central features of asthma. This study will give a better understanding of how the inflammation is caused and information for new drug targets.

Funding Amount $AUD 495,380.95

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant