Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1049459]Researchers: A/Pr Daniel Hatters (Principal investigator) , A/Pr Till Boecking
Brief description Huntington disease results from a mutation that causes the Htt protein to become abnormally sticky and form toxic clusters in neurons. Cells have natural defences to clustering with proteins called chaperones, which are exciting therapeutic targets. This project will examine how chaperones defend against toxic Htt clustering with cutting-edge imaging technologies. The knowledge gained will aid in designing therapeutic strategies that stimulate the defence processes and suppress the clusters.
Funding Amount $AUD 590,103.59
Funding Scheme Project Grants
Notes Standard Project Grant
- nhmrc : 1049459
- PURL : https://purl.org/au-research/grants/nhmrc/1049459
