The role of the homeobox transcription factor Hhex in haematopoiesis and leukaemia [ 2015 - ]

Research Grant

Researchers: A/Pr Matthew McCormack (Principal investigator)

Brief description We have shown that the Haematopoietically expressed homeobox (Hhex) protein plays important roles in development of immune cells. In addition, Hhex is required for development and maintenance of Acute Myeloid Leukemia (AML). This project will further investigate the requirement of Hhex in human AML, potentially identifying a new therapeutic target in this poor-prognosis cancer subtype. In addition, we will identify critical cofactors and targets of Hhex, revealing new therapeutic strategies.

Funding Amount $603,813.00

Funding Scheme Project Grants

Notes Standard Project Grant