grant

Role of the hepatitis C virus glycoprotein E2 variable regions in viral entry and antibody mediated neutralization. [ 2009 - 2011 ]

Also known as: How variable regions in HCV E2 modulate glycoprotein function.

Funded by National Health and Medical Research Council
Managed by Macfarlane Burnet Institute for Medical Research and Public Health
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/543113]

Researchers: A/Pr Heidi Drummer (Principal investigator) ,  Dr Pantelis Poumbourios

Brief description The first stage of Hepatitis C Virus replication involves attaching to liver cells. This study is aimed at understanding how the virus attaches to liver cells and how antibodies raised during infection, block this interaction. In addition, this study aims to examine how the virus modulates its structure to evade the immne system, allowing the virus to establish chronic infections. The results of this study will guide future vaccine design for HCV.

Funding Amount $AUD 542,462.24

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

Click to explore relationships graph
Help

Related Organisations

Related People

Subjects
Antibody | Applied Immunology (Incl. Antibody Engineering, Xenotransplantation and T-Cell Therapies) | Biomedical and Clinical Sciences | Hepatitis C Virus | Immunology | acute hepatitis | chronic disease caused by hepatitis C virus infection | development of HCV vaccine | envelope glycoprotein | prevention of infectious disease | viral fusion | viral hepatitis |
Identifiers
Viewed: [[ro.stat.viewed]]
Saved to MyRDA Save to MyRDA
ACN 633 798 857