The role of excitotoxicity in mediating distal axonal degneration in ALS [ 2011 - 2014 ]

Research Grant

Researchers: Prof Tracey Dickson (Principal investigator) ,  A/Pr Anna King ,  Prof James Vickers ,  Prof Roger Chung

Brief description Amyotrophic lateral sclerosis (ALS), the major cause of motor neuron disease, is a devastating diseasse for which there is no cure. There have been significant advances in understanding the pathology of ALS yet we still don’t know what causes the dying back of spinal motor neurons. We have new evidence that suggests that ALS may, in part, be caused by excitotoxcity - or over stimulation - of neurons in the spinal cord. We will follow this lead using a range of cutting edge experimental models.

Funding Amount $AUD 392,952.52

Funding Scheme Project Grants

Notes Standard Project Grant