Role of epigenomic changes in conferring hyperglycemic memory [ 2013 - 2015 ]

Research Grant

Researchers: Prof Assam El-Osta (Principal investigator) ,  Dr Christos Tikellis ,  Prof Merlin Thomas

Brief description The major burden of type I diabetes remains its vascular complications including diabetes-accelerated athersclerosis. Despite improved glucose control, diabetic individuals develop complications as a result of prior poor glycemic control. Although the development and progression of these diabetic complications is strongly associated with mean levels of glucose, recent studies suggest that the deleterious effects of early exposure to high levels of glucose persist for years even after treatment has returned glucose levels towards normal.

Funding Amount $AUD 636,146.31

Funding Scheme Project Grants

Notes Standard Project Grant