Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/633225]Researchers: Prof Phillip Robinson (Principal investigator)
Brief description Neurons communicate by neurotransmitter release from synaptic vesicles stored in nerve endings. There is a finite vesicle number, so they are recycled (endocytosis) by dynamin. Our aim is to reveal the molecular mechanisms underlying endocytosis to better understand diseases of the synapse like epilepsy. We propose that two forms of the dynamin gene mediate two forms of endocytosis, one of which is activated only under conditions of high neuronal firing, such as occurs during a seizure.
Funding Amount $AUD 905,985.83
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 633225
- PURL : https://purl.org/au-research/grants/nhmrc/633225
