grant

A role for double-stranded RNA-dependent protein kinase in regulating Nod-like receptor signaling for modulating colitis and colitis-associated cancer. [ 2013 - 2015 ]

Also known as: Understanding the mechanism of development of inflammatory bowel diseases and their associated colorectal cancers for establishing new effective treatment against these diseases

Funded by National Health and Medical Research Council
Managed by Monash University
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1052730]

Researchers: Dr Howard Yim (Principal investigator)

Brief description Inflammatory bowel disease (IBD) and Colorectal cancers (CRC) are commonly found in developed countries like Australia. In spite of improved treatment for IBD and CRC, it is still not known why many patients are still not responsive to these therapies. Therefore, this proposed project aims to use genetically modified mice and molecular biology techniques to understand the pathogenesis of these diseases and to find an alternative new treatment for these diseases.

Funding Amount $AUD 230,600.57

Funding Scheme Early Career Fellowships

Notes Australia-China Exchange ECF

Click to explore relationships graph
Help

Related Publications

Related Organisations

Related People

Subjects
Immunology | Medical and Health Sciences | Tumour Immunology | colitis | colorectal cancer | colorectal cancer treatment | immune regulation | immune-mediated inflammation | inflammation | inflammatory bowel disease (IBD) | interleukins (IL) | macrophages | ulcerative colitis |
Identifiers
Viewed: [[ro.stat.viewed]]
Saved to MyRDA Save to MyRDA
ACN 633 798 857