grant

The role of diffuse myocardial fibrosis in myocardial stiffness [ 2014 - 2019 ]

Also known as: The role of cardiac muscle scar in cardiac muscle stiffness

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1072751]

Researchers: Dr Leah Iles (Principal investigator)

Brief description Collagen, a major component of scar, accumulates in some hearts and we may expect this to increase stiffness, threatening heart function. We have shown poor heart relaxation correlates with increased collagen on heart magnetic resonance imaging (MRI). We aim to establish a link between MRI findings and direct measures of heart stiffness, a link between degree of stiffness and amount of collagen and effects of anti-fibrotic therapy on heart collagen; aiding diagnosis, prognosis and outcome.

Funding Amount $AUD 378,032.85

Funding Scheme Early Career Fellowships

Notes Australian Clinical Research ECF

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Identifiers
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ACN 633 798 857