The Role of Dendritic mRNA Decay in Synaptic Plasticity & Cognition [ 2018 - ]

Research Grant

Researchers: Mr Michael Notaras (Principal investigator)

Brief description Schizophrenia is characterized by abnormal contacts between brain cells, known as synapses. Maintenance of synapses requires the translation of gene products, termed mRNA, into protein. Schizophrenia has been associated with genes involved in the degradation of mRNA, which buffers translation and thus protein levels. My research therefore seeks to study the role of mRNA decay in synaptic structure, synaptic function and cognition.

Funding Amount $408,768.00

Funding Scheme Early Career Fellowships

Notes CJ Martin Biomedical ECF