The role of cross-reactive T cells in severe lung disease following viral respiratory infections [ 2015 - 2018 ]

Research Grant

Researchers: Prof Anthony Purcell (Principal investigator) ,  A/Pr Thomas Kotsimbos ,  Dr Nicole Mifsud

Brief description Why do some patients clinically deteriorate at a greater rate than others during acute respiratory viral infections despite similar or identical clinical management? One explanation is the reactivation immunity towards ubiquitous viruses that then go on to cross-react against the new respiratory pathogen leading to an overly aggressive and destructive response in the lung. We will examine this potential of existing anti-viral immune responses to exacerbate disease in lung transplantation, as suc

Funding Amount $AUD 1,003,390.81

Funding Scheme Project Grants

Notes Standard Project Grant