grant

The role of Crim1 in growth factor activity and cell motility/adhesion. [ 2007 - 2009 ]

Also known as: The role of a novel protein, Crim1, in development and disease

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/455972]

Researchers: Prof Melissa Little (Principal investigator)

Brief description Crim1 is a novel protein which appears to regulate the activity of growth factors and therefore affects the normal development of a number of organs. It is particulrly involved in normal development of blood vessels. A greater understanding of how growth factor activity is modulated by Crim1 will have significance to almost every developmental and disease state involving such growth factors. The potential for Crim1 to link the activity of several distinct growth factor pathways may explain tissue specific differences in growth factor responses. These basic advances in understanding will have implications for many disease states, including renal disease, vascular disease and cancer.

Funding Amount $AUD 600,065.08

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857