grant

The role of chemokine networks in severe malaria and the control of parasite density [ 2012 - 2014 ]

Also known as: Role of inflammatory factors of severe malaria in the control of parasite burden

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1031212]

Researchers: Dr Diana Hansen (Principal investigator)

Brief description Two contributing factors have been identified as the main determinants of severe malaria: high parasite densities and host inflammatory responses. To date it is not clear whether inflammation is a cause or a consequence of high parasite densities. We have identified a new biomarker (IP-10) of disease severity in a malaria-endemic area of Papua New Guinea that is associated with high parasite densities. Here we will decipher the mechanisms by which IP-10 contributes to the development of high parasite burden and severe malaria.

Funding Amount $AUD 620,731.92

Funding Scheme Project Grants

Notes Standard Project Grant

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