Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1085403]Researchers: Prof Christopher Parish (Principal investigator)
Brief description The immune system can recognise a large array of foreign pathogens without reacting to self-components. For this to occur T cells, the main mediators of immunity, must be made to tolerate self-molecules as they develop in the thymus. We have identified a novel interaction between a molecule called CD8 on T cells and a complex carbohydrate called heparan-sulfate, which helps auto-reactive T cells to be eliminates in the thymus. The aim of this project is to further investigate this phenomenon.
Funding Amount $AUD 649,135.63
Funding Scheme Project Grants
Notes Standard Project Grant
- nhmrc : 1085403
- PURL : https://purl.org/au-research/grants/nhmrc/1085403
