Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1010128]Researchers: Prof Michael Cowley (Principal investigator)
Brief description Melanocortin neurons control body weight and are regulated by leptin. In obesity leptin cannot regulate the melanocortin system. We will test if leptin action on melanocortin neurons is limited by increased expression of suppressor of cytokine signalling 3 (SOCS3) in obese mice. As an alternative we will test if there are changes in the blood brain barrier, or an increased density of support and immune cells around melanocortin neurons of obese mice that might restrict inputs to these neurons.
Funding Amount $AUD 730,123.10
Funding Scheme Project Grants
Notes Standard Project Grant
- nhmrc : 1010128
- PURL : https://purl.org/au-research/grants/nhmrc/1010128
