The role of Ap2a2 in self-renewal of haematopoietic and leukemic stem cells [ 2011 - 2013 ]

Research Grant

Researchers: A/Pr Stephen Ting (Principal investigator) ,  Prof Guy Sauvageau ,  Prof Sarah Russell

Brief description The daily replenishment of the blood system is dependent on the blood stem cell. A unique property of these stem cells is self-renewal where the stem cell function is preserved, whilst other daughter cells continue to divide. Our research investigates the molecular mechanisms that regulate stem cell self-renewal. This work has potential clinical application on at least two levels: expansion of stem cells for transplantation, and for attacking abnormal cancer cell self-renewal pathways.

Funding Amount $AUD 579,171.67

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant