The Role of Androgens In Female Physiology [ 2003 - 2005 ]

Research Grant

Researchers: Prof David Handelsman (Principal investigator) ,  A/Pr Peter Illingworth ,  Dr Charles Allan ,  Dr Julie Mcmanus ,  Prof Jeffrey Zajac

Brief description This study is aiming to develop an unique mouse model in which to study the question whether testosterone plays an essential role in female reproductive and general health. It will develop a genetic mouse model for a biological state of complete resistance to the effects of androgens. Such mice and humans are well known among genetic males but this cannot occur naturally among genetic female mammals. By creating such a mouse line, this project will be able to test for the first time indetail whether testosterone has an impotant role in the development and function of the ovary and of other female tissues such as bone, muscle and the brain.

Funding Amount $AUD 378,750.00

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant