The role of Aire in immunological tolerance and autoimmunity [ 2008 - 2010 ]

Research Grant

Researchers: A/Pr Frank Alderuccio (Principal investigator) ,  Dr Francois-Xavier Hubert ,  Prof Hamish Scott

Brief description The immune system is designed to protect us from foreign pathogens such as bacteria, viruses and parasites. This is achieved through lymphocytes which recognise foreign pathogens. However in 5-6% of the population the immune system attacks the host and induces autoimmunity. We aim to understand the mechanisms which control the production of self-reacting lymphocytes and how we may reduce the incidence of autoimmunity.

Funding Amount $AUD 434,134.94

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant