Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/510148]Researchers: Prof Brett Garner (Principal investigator) , A/Pr Woojin Kim , Prof Glenda Halliday
Brief description Alzheimer's disease (AD) prevalence is rising and the contributing factors are poorly understood. Recent research shows that cholesterol regulates the production of neurotoxic amyloid-beta peptide (Abeta). We will study a class of proteins, ABC transporters, that we believe regulate neuronal cholesterol and Abeta metabolism. We will use isolated brain cells, human brain tissue and genetically engineered mice in order to define how cholesterol influences AD and identify new treatment options.
Funding Amount $AUD 557,582.81
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 510148
- PURL : https://purl.org/au-research/grants/nhmrc/510148
