RNA-mediated control of HIV gene expression [ 2011 - 2013 ]

Research Grant

Researchers: Prof Damian Purcell (Principal investigator) ,  A/Pr Peter Revill ,  Prof Sharon Lewin

Brief description Current combination antiviral therapy can't cure an HIV infection because long-lived T-cells carrying latent HIV DNA can rekindle the infection when drugs are removed. We will study elements in HIV genetic code that control expression of HIV proteins from latent HIV. A detailed molecular understanding of the structure and function of these HIV RNA elements and the viral and host cell factors that interact with them will expose new targets for therapy of latent HIV.

Funding Amount $AUD 590,426.75

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant