grant

RNA-DIRECTED EPIGENETIC REMODELLING IN CANCER [ 2011 - 2013 ]

Also known as: ROLE OF NON-CODING RNA IN CARCINOGENESIS

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1010620]

Researchers: Prof Susan Clark (Principal investigator)

Brief description Epigenetics describes how genes can be turned off or on without changing the DNA sequence. Epigenetics plays a major role in cancer development. In this proposal we are investigating a novel hypothesis that in cancer a similar mechanism to imprinting USING NON-CODING RNA is triggered and this promotes the suppression of clusters of genes. The results from this proposal will have major implications to our understanding of gene regulation in cancer and will have important therapeutic value for cancer treatment.

Funding Amount $AUD 718,770.82

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857