(Re)wiring a stem cell: Deciphering the molecular mechanism underpinning lineage propensity [ 2017 - 2019 ]

Research Grant

Researchers: Prof Patrick Tam (Principal investigator) ,  Dr Dmitry Ovchinnikov ,  Prof Ernst Wolvetang ,  Prof Justin Cooper-White

Brief description This project explores the response of the stem cells to cues that direct how they turn into specific type of cells that is suitable for clinical use. Specifically, a set of driver genes whose activity can foretell the outcome of cell differentiation will be identified. By modulating the maintenance conditions, iPSCs lines may be tailored for specific applications in stem cell therapy and disease modelling for the assessment of treatment efficacy.

Funding Amount $AUD 876,214.92

Funding Scheme Project Grants

Notes Standard Project Grant