Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/633252]Researchers: Prof Helge Rasmussen (Principal investigator) , A/Pr Craig Mclachlan , Prof Gemma Figtree
Brief description Heart failure is a debilitating condition characterised by a decreased heart pump function. Raised Na+ levels and increased oxidative stress in cardiac cells are important in its causation. While traditional antioxidants are not useful in treatment, we have found that a group of drugs designed to induce weight loss can reverse oxidative inhibition of the mechanism that pumps Na+ out of heart cells. The effect of these drugs on the Na+ pumping mechanism and heart failure will be examined.
Funding Amount $AUD 533,541.03
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 633252
- PURL : https://purl.org/au-research/grants/nhmrc/633252
