Revealing how the mammalian preimplantation embryo undergoes compaction [ 2014 - 2017 ]

Research Grant

Researchers: Dr Nicolas Plachta (Principal investigator) ,  Prof John Carroll (Principal investigator)

Brief description The first morphological process critical for mammalian development is embryo compaction. During compaction, cells change their morphology from rounded to wedge-like. The mechanisms controlling embryo compaction remain unclear. We recently discovered that during compaction, cells extend long membrane protrusions on top of each other. In this Project we will establish the role of these protrusion in controlling embryo compaction and reveal the mechanisms underlying their formation.

Funding Amount $AUD 705,102.57

Funding Scheme Project Grants

Notes Standard Project Grant