Retroviral Expression Cloning Using an Arrayed Full Length cDNA Gene Set [ 2006 - 2010 ]

Research Grant

Researchers: Prof Thomas Gonda (Principal investigator)

Brief description The sequencing of the human genome has revealed the blueprint for life, but the identities and-or functions of the majority of genes remain unknown. Here we propose to establish a radically modified retroviral expression cloning system that will, in principle, allow identification of all genes that confer a particular dominant phenotype. To do this we will establish an arrayed retroviral library of sequence-verified genes covering the entire human transcriptome. This technology will be used to identify genes involved in a wide range of medically-important biological processes.

Funding Amount $AUD 1,841,500.00

Funding Scheme NHMRC Strategic Awards

Notes Medical Bioinformatics,Genomics & Proteomics Grant