Resolving and targeting the complex molecular mechanisms underlying GPCR signalling [ 2018 - 2021 ]

Research Grant

Researchers: Prof Ross Bathgate (Principal investigator) ,  A/Pr Paul Gooley ,  Dr Daniel Scott ,  Dr David Chalmers ,  Dr Michael Griffin

Brief description Receptors are located on the surface of all human cells to allow our cells to respond to their environment. Over 30% of prescription drugs act through particular receptors called GPCRs, however effective drugs without side effects are difficult to develop because we do not have a deep understanding of how GPCRs transmit complex signals. In this proposal we seek to resolve the atomic-level details of GPCR signalling to assist in the development of better drugs for a diverse range of diseases.

Funding Amount $AUD 1,086,369.58

Funding Scheme Project Grants

Notes Standard Project Grant