Rescuing the dystrophin-glycoprotein complex to protect muscles from wasting conditions [ 2018 - ]

Research Grant

Researchers: Prof Gordon Lynch (Principal investigator) ,  A/Pr Paul Gregorevic

Brief description Existing medical strategies to counteract severe muscle wasting disorders are compromised because of dysfunctional signalling around a cluster of proteins called the dystrophin-glycoprotein complex (DGC) located at the muscle membrane. To address this significant unmet medical need, this proposal investigates novel approaches to retain or restore DGC integrity at the muscle membrane with the goals of preserving and protecting muscles during serious wasting conditions.

Funding Amount $833,340.00

Funding Scheme Project Grants

Notes Standard Project Grant