Reprogramming macrophage function in the elderly to rescue impaired inflammatory responses to muscle injury [ 2016 - 2018 ]

Research Grant

Researchers: Dr Connie Jackaman (Principal investigator) ,  Dr Danielle Dye ,  Dr Hannah Crabb

Brief description Muscle injury in the elderly often takes longer to heal than in younger people, however the cells responsible for this delayed healing are not well understood. Key inflammatory cells required for muscle repair in young hosts are macrophages. However, during aging we have shown that macrophage function is altered, but the mechanism is unknown. This project aims to determine the mechanisms behind age-related changes to macrophages and whether they can be targeted to improve elderly muscle repair.

Funding Amount $AUD 422,669.60

Funding Scheme Project Grants

Notes New Investigator Grant