grant

Renal AT2R are a therapeutic target for the treatment of hypertension in women [ 2010 - 2012 ]

Also known as: His and Hers of kidney function

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/606652]

Researchers: Prof Kate Denton (Principal investigator) ,  Prof Robert Widdop Prof Roger Evans

Brief description Being female is associated with better renal function, resistenace to renal injury and hypertension, but it is not understood why. Our work demonstrates that women have more angiotensin type 2 receptors (AT2R) in the kidney then men. In men AT2R have been suggested to protect against hypertension and renal damage. We predict that the effects of AT2R stimulation will be greater in women and therefore the protective benefits greater.

Funding Amount $AUD 605,939.34

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857