grant

Release and action of anterogradely transported BDNF from sensory nerve terminals in the spinal cord [ 2000 - 2002 ]

Also known as: Release of the growth factor, BDNF, from nerves in the spinal cord

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/102105]

Researchers: E/Pr Robert Rush (Principal investigator)

Brief description Neurotrophic factors are powerful agents found in very low amounts throughout the nervous system. Their role is to keep nerves alive, to assist in connecting nerves together and to help maintain the health of nerves. Usually this is achieved by each factor being bound at the end of the long nerve processes and transported back to the nucleus to regulate the metabolism of the nerve. We have discovered one factor, the protein Brain Derived Neurotrophic Factor or BDNF, in one nerve type which is transported in the opposite direction. The project outlined plans to demonstrate the function of this unique transport by showing how BDNF can be released from nerves to act on neighboring cells.

Funding Amount $AUD 204,674.96

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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