Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/142008]Researchers: Prof Michael Feneley (Principal investigator)
Brief description An increase in muscle bulk (hypertrophy) of the major pumping chamber of the heart, the left ventricle, occurs as a compensatory mechanism to maintain cardiac function in a wide variety of common cardiovascular diseases, such as hypertension. Nevertheless, this compensatory mechanism appears to be strongly associated with an increased risk of death from cardiovascular disease. Consequently, the prevention or reversal of left ventricular hypertrophy is one of the major goals of the treatment of patients with cardiovascular disease. This project aims to improve our understanding of the complex chemical messengers in the heart muscle that control the development of hypertrophy to provide a basis for more specific drug treatments to control this process, with the aim of reducing the morbidity and mortality associated with hypertrophy.
Funding Amount $AUD 309,536.72
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 142008
- PURL : https://purl.org/au-research/grants/nhmrc/142008
