Regulatory mechanisms of antibody cytotoxicity for cancer therapy [ 2009 - 2011 ]

Research Grant

Researchers: Prof Andrew Scott (Principal investigator) ,  A/Pr Paul Ramsland ,  Prof Jeffrey Ravetch

Brief description Use of antibodies for cancer therapy, where a protein is made in the laboratory to recognize and act on cancer cells that have a target antigen, has emerged as an important therapeutic area in oncology. The lewis-y (Ley) antigen is found in over 70% of epithelial cancers. We have developed an antibody against Ley (hu3S193) which can target cancer cells. Our research is aimed at developing optimal cancer cell killing by our anti-Ley antibody.

Funding Amount $AUD 566,087.19

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant