Regulation of toxoplasma by the NLRP1 inflammasome [ 2014 - 2016 ]

Research Grant

Researchers: Dr Seth Masters (Principal investigator) ,  A/Pr Christopher Tonkin

Brief description Toxoplasmosa is an endemic pathogen worldwide, approaching 80% of the population in some areas, with a large burden of disease, particularly of immunocompromised and pregnant individuals. Our preliminary data identifies a receptor protein in immune cells that detects Toxoplasma. This can defeat the parasite, but also causes pathology for the host. The outcome of our project will work out what part of Toxoplasma is recognized by this receptor, with significance for the treatment of Toxoplasmosis.

Funding Amount $AUD 623,070.46

Funding Scheme Project Grants

Notes Standard Project Grant