grant

Regulation of T follicular helper cell development and effector function in health and disease [ 2010 - 2012 ]

Also known as: Understanding T-cell dependent B-cell responses

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/596813]

Researchers: Prof Stuart Tangye (Principal investigator) ,  A/Pr David Fulcher Dr Cindy Ma Dr Elissa Deenick Prof Matthew Cook

Brief description Immune cells mature into distinct populations with specialized functions. One subsets are T follicular helper (TFH) cells which are important for instructing B cells to produce antibodies following infection or vaccination. The means by which TFH cells are generated are unknown. We will determine mechanisms whereby TFH cells are produced and how they function. We hope to design approaches that will modulate the function of TFH cells in cases of immunodeficiencies, autoimmunity or vaccination.

Funding Amount $AUD 419,197.81

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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