Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/606407]Researchers: Prof David Jans (Principal investigator) , Prof Philip Bardin , Prof Reena Ghildyal
Brief description Respiratory syncytial virus (RSV) is the major cause of viral pneumonia in infants and the elderly, causing more deaths in winter than influenza. We have observed RSV M protein in the nucleus of infected host cells where it inhibits host cell transcription. We propose to investigate the regulation of nuclear localisation of M by phosphorylation and binding to cellular factors and its importance to RSV pathogenesis. The results will relate strongly to future drug and vaccine development.
Funding Amount $AUD 580,195.62
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 606407
- PURL : https://purl.org/au-research/grants/nhmrc/606407
