grant

Regulation of the quality of DNA repair by timing in the cell cycle [ 2011 - 2013 ]

Also known as: When and how do cells repair damaged genes?

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1012291]

Researchers: Dr Christopher Jolly (Principal investigator)

Brief description During responses to infection or immunisation, antibody-producing _B� cells mutate their antibody genes at extreme rates. Rare mutations which improve the antibodies are selected by competition between B cells favouring those which make the best antibodies: Darwinian evolution on extreme _fast-forward�. We aim to understand this process because it is essential for normal immunity and effective vaccination, and because when it goes wrong, it can cause aggressive human cancers.

Funding Amount $AUD 468,794.84

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857