grant

Regulation of PtdIns(3,4)P2 signalling by inositol polyphosphate 4-phosphatase-1 [ 2008 - 2010 ]

Also known as: regulation of cell differentiation and cancer by lipid phosphatases

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/491029]

Researchers: Prof Christina Mitchell (Principal investigator)

Brief description Normally cells only divide when they receive a stimulus such as from a hormone or growth factor. One of the signaling pathways which responds to growth factor stimulation is the PI3-kinase pathway. This pathway has been implicated in many different human cancers which occur when cells divide uncontrollably and invade into the surrounding tissues. We have idenitified a novel enzyme called the inositol polyphosphate 4-phosphatase that appears to regulate cell proliferation and differentiation.

Funding Amount $AUD 557,939.08

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857