Regulation of the placental renin-angiotensin system by microRNAs; implications for pregnancies complicated by placental insufficiency? [ 2013 - 2016 ]

Also known as: Regulation of the placental renin-angiotensin system and placentation

Research Grant

[Cite as]

Researchers: E/Pr Eugenie Lumbers (Principal investigator) ,  Prof Brian Morris Prof Fiona Broughton Pipkin Prof Claire Roberts

Brief description Intrauterine growth restriction (IUGR) and preeclampsia (PrE) are life threatening to mother and baby, making the baby susceptible to disease as an adult. One of the major causes of PreE and IUGR is placentation. Placentation is affected by the placental renin-angiotensin system (RAS), which is controlled by microRNAs. We will describe these microRNAs, what controls them; determine their expression and RAS expression in normal pregnancy, IUGR and PrE, thus providing novel biomarkers for their early detection.

Funding Amount $AUD 483,058.91

Funding Scheme Project Grants

Notes Standard Project Grant

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