REGULATION OF LIPID METABOLISM IN SKELETAL MUSCLE BY IDOL – a novel degrader of the very low density lipoprotein receptor [ 2015 - ]

Research Grant

Researchers: Dr Anna Calkin (Principal investigator)

Brief description More than 1 in 5 Australians are estimated to have increased levels of fats (triglycerides; TGs) in the blood, commonly due to excess dietary intake or genetics. The excess TGs are deposited in skeletal muscle where they can cause insulin resistance, increasing the risk of developing diabetes, the fastest growing chronic condition in Australia. I will examine whether a recently identified protein, IDOL, can reduce accumulation of TGs in skeletal muscle and protect against insulin resistance.

Funding Amount $536,260.00

Funding Scheme Project Grants

Notes New Investigator Grant