Research Grant
[Cite as http://purl.org/au-research/grants/nhmrc/1006588]Researchers: Prof Bryan Williams (Principal investigator) , Dr Dakang Xu
Brief description Toll-like receptors (TLRs) play an essential role in innate immune responses and are involved in initiating tumourigenesis via inflammatory pathways. We have shown that the transcription factor ATF3 is a negative regulator of TLR signalling. We will study how modulation of the activity of ATF3 affects the inflammatory response and tumour progression. This will provide a molecular basis on which to design therapeutic reagents for the treatment of cancer.
Funding Amount $AUD 473,469.96
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- PURL : http://purl.org/au-research/grants/nhmrc/1006588
- nhmrc : 1006588