grant

Regulation of hypothalamic insulin & leptin signalling by TCPTP [ 2011 - 2014 ]

Also known as: Regulation of hypothalamic signalling by TCPTP

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1002709]

Researchers: Prof Tony Tiganis (Principal investigator) ,  Prof Michael Cowley

Brief description Insulin & leptin signal in the brain to lower blood glucose, suppress food intake, increase activity & increase energy expenditure. Obesity diminishes the abilities of insulin & leptin to signal. This proposal will determine if the enzyme TCPTP terminates insulin & leptin signaling in the brain. Our studies will provide insight into the molecular causes of obesity & may identify a novel therapeutic target for the treatment of obesity & type 2 diabetes.

Funding Amount $AUD 758,504.55

Funding Scheme Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857