Regulation of haematopoietic stem cells through histone modifications [ 2015 - 2017 ]

Research Grant

Researchers: A/Pr Anne Voss (Principal investigator) ,  A/Pr Tim Thomas

Brief description The genetic material is packaged in the cell nucleus with histone proteins. Modifications of histones determine if a particular area of the genome is active or repressed. We are investigating a family of histone modifying proteins, the MYST proteins. Mutations in these proteins cause intellectual disability and blood cancer. In this project we examine the role of MYST2 in blood stem cells. Knowledge gained may become the basis for the development of drugs for the treatment of cancer.

Funding Amount $AUD 797,014.58

Funding Scheme Project Grants

Notes Standard Project Grant