grant

Regulation of gene expression in mitochondrial disease [ 2009 - 2012 ]

Also known as: Mitochondrial gene expression

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/572513]

Researchers: A/Pr Aleksandra Filipovska (Principal investigator) ,  A/Pr Oliver Rackham

Brief description Mitochondrial diseases affect 4000 children every year and most of these children do not reach adulthood. These diseases result from defects in mitochondria, energy producing compartments within cells. We have discovered a protein that controls mitochondrial gene expression and used it to rescue dysfunction in cells from patients with mitochondrial disease. We will determine its function and role in cell health, allowing us to evaluate its importance in mitochondrial disease.

Funding Amount $AUD 338,362.94

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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