Regulation of endogenous heart regeneration by an anti-fibrotic microRNA. [ 2015 - 2018 ]

Research Grant

Researchers: A/Pr Enzo Porrello (Principal investigator) ,  Dr James Hudson

Brief description In contrast to the adult heart, the newborn heart undergoes scarless healing following a heart attack. The molecular mechanisms that govern heart regeneration in newborn mammals are not fully understood. The goal of the current study is to determine the role of a recently identified family of molecules known as microRNAs in the regulation of scarless healing. We propose a novel strategy for re-activation of microRNAs in the adult heart to promote regeneration following heart attack.

Funding Amount $AUD 440,949.75

Funding Scheme Project Grants

Notes Standard Project Grant