grant

Regulation of cardiac hypertrophy a at the level of ribosome biogenesis [ 2008 - 2010 ]

Also known as: Cardiac hypertrophy and ribosome biogenesis

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/508907]

Researchers: Prof Ross Hannan (Principal investigator) ,  A/Pr Elizabeth Woodcock Prof Walter Thomas

Brief description A major feature of cardiac hypertrophy (enlarged heart) is accelerated cell growth and protein synthesis. This results from increased synthesis of ribosomes (the protein synthetic machinery). This study will examine a factor termed UBF whose activity is critical for the regulation of ribosome synthesis. Understanding the mechanisms controlling UBF function will provide new avenues in which to develop therapeutics to combat hypertrophic heart disease.

Funding Amount $AUD 634,587.35

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857