grant

Regulation of body composition and glucose homeostasis by the adaptor protein Grb10. [ 2008 - 2010 ]

Also known as: Regulation of hormone and growth factor action in muscle and fat.

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/481335]

Researchers: Prof Roger Daly (Principal investigator) ,  Andrew Ward Dr Peter Currie Prof Gregory Cooney

Brief description Resistance to the hormone insulin underlies the development of Type 2 Diabetes. Loss of muscle mass in the elderly contributes to insulin resistance. Recently we identified Grb10 as a new regulator of insulin action and muscle mass. In this proposal, we aim to study how Grb10 affects development and growth of muscle and fat, and the underlying molecular mechanisms. This may lead to new strategies for improving body composition and treating the insulin resistance associated with Type 2 Diabetes.

Funding Amount $AUD 617,256.35

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857