Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1124288]Researchers: Dr Joanne O'Donnell (Principal investigator)
Brief description Excessive cell death can lead to chronic inflammation and autoimmunity. Cells can die by different mechanisms including necroptosis which causes inflammation, and apoptosis which does not. Recent studies show that caspases, a component of the apoptosis pathway which accelerate cell death, also prevent immune activation by dying cells. I will investigate whether caspases contribute to autoimmune disease and whether caspases can dampen the inflammation that occurs during necroptotic cell death.
Funding Amount $AUD 327,192.08
Funding Scheme Early Career Fellowships
Notes Peter Doherty Biomedical ECF
- nhmrc : 1124288
- PURL : https://purl.org/au-research/grants/nhmrc/1124288
