The Regulation of Antibody: A Systems Approach [ 2009 - 2013 ]

Research Grant

Researchers: Prof Philip Hodgkin (Principal investigator) ,  Prof David Tarlinton ,  Prof Lynn Corcoran ,  Prof Stephen Nutt

Brief description Antibodies are made by B-cells and are essential for a functional immune system. B cells circulate in the body, and, when they encounter an invader, they mature into antibody-producing cells (ASC). A small proportion of the cells become “memory” cells with the potential to become ASC should the same infection occur in the future. This is the basis of vaccination. This program aims to understand how a B cell changes into an ASC. We aim eventually to be able to improve vaccines and understand diseases such as allergy, lupus, arthritis and leukaemia to develop novel therapies.

Funding Amount $AUD 8,111,314.81

Funding Scheme Programs

Notes Program Grant