grant

Regulation of actin polymerization during malaria parasite invasion of the human erythrocyte [ 2008 - 2010 ]

Also known as: Actin regulation in the malaria parasite

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/516747]

Researchers: Dr Jake Baum (Principal investigator) ,  A/Pr Christopher Tonkin

Brief description Malaria parasites depend on successful invasion of red blood cells for their survival. Invasion is powered by a molecular motor based on two key proteins: actin and myosin. Non-specific drugs that inhibit parasite actin block invasion, demonstrating how important its regulation is to parasite success. This project will study several newly identified malaria actin-regulators, aiming to identify new drug targets that will block malaria actin function, stop motility and as such prevent disease.

Funding Amount $AUD 318,147.04

Funding Scheme NHMRC Project Grants

Notes New Investigator Grant

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